Taxonomer is an ultra-fast and interactive metagenomics analysis software that dramatically improves the accuracy and speed of universal microorganism detection by Next Generation Sequencing (NGS).
Taxonomer enables universal, real-time detection of viruses, bacteria, and fungi through an easy-to-use web interface.
For every sequencing read, Taxonomer provides the best taxonomic classification that is supported by the reference database through both, nucleic acid and protein-based classification for improved detection.
With RNA-seq data, Taxonomer also provides host mRNA expression profiles.
Taxonomer is highly tolerant to sequencing errors, more sensitive, and more accurate, and faster than comparable tools.
Taxonomer is developed in collaboration with University of Utah, ARUP Laboratories and IDbyDNA.
In a paper titled “Taxonomer: an interactive metagenomics analysis portal for universal pathogen detection and host mRNA expression profiling” published in Genome Biology, Dr. Schlaberg et al demonstrated the ability of Taxonomer to analyze the sequences of all nucleic acids in a clinical specimen (DNA and RNA) and to detect pathogens, as well as profile the patient’s gene expression, in a matter of minutes.
In another paper published in the Journal of Clinical Microbiology, Dr. Schlaberg and his collaborators demonstrated that high-throughput sequencing in combination with Taxonomer can reliably detect viral pathogens with high agreement to an FDA-approved respiratory viral PCR panel, and identify previously missed viral pathogens, in patient samples.